This repository is a community-curated collection of resources for applying ChatGPT and other Large Language Models (LLMs) in computational biology. It targets bioinformaticians and researchers, providing links to prompt collections, applications, tutorials, and discussions to facilitate the adoption of LLMs in biological research.

How It Works

The repository functions as a curated list of external links, categorized by application type and topic. It aggregates resources such as prompt collections for data science and bioinformatics, tools integrating LLMs with bioinformatics pipelines (e.g., BioChatter, BioGPT), and guides on prompt engineering and LLM fundamentals. The community-driven approach allows for continuous expansion and relevance.

Quick Start & Requirements

This is a curated list, not a software package. To utilize the resources, users will need access to LLM APIs (like OpenAI's) or specific tools mentioned. Links to relevant projects, tutorials, and discussions are provided throughout the README.

Highlighted Details

• Comprehensive sections on prompt engineering best practices and LLM technical overviews.
• Includes bioinformatics-specific applications like scGPT and BioGPT, and tools for integrating LLMs with biological data pipelines.
• Features community discussions on Reddit regarding LLMs in bioinformatics careers.
• Provides links to resources for improving code readability, writing code efficiently, and data visualization using LLMs.

Maintenance & Community

The repository is community-maintained via GitHub Pull Requests. It encourages contributions from the computational biology community. Links to relevant discussions (e.g., Reddit) are provided.

Licensing & Compatibility

The repository itself is licensed under an unspecified license, but it primarily links to external resources, each with its own licensing. Users must verify the licenses of individual tools and datasets. Compatibility for commercial use depends on the licenses of the linked LLM services and software.

Limitations & Caveats

As a curated list, the quality and maintenance of linked resources are external to this repository. Some linked applications may be experimental, freemium, or require specific API access. The rapid evolution of LLMs means some linked information may become outdated.